2-((7-Chloro-3-cyclohexyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide CAS 778619-76-4
| CAS No. | 778619-76-4 |
| Molecular Formula | C22H27ClN4O2S |
| Molecular Weight | 446.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-((7-Chloro-3-cyclohexyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-((7-Chloro-3-cyclohexyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 778619-76-4), a certified reference material (molecular formula C22H27ClN4O2S, MW 446.99 g/mol) for analytical method development and quality control.
The molecular framework of 2-((7-Chloro-3-cyclohexyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (C22H27ClN4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27ClN4O2S |
| Molecular Weight | 446.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-N1,N1,N3,N3-tetraphenylbenzene-1,3-diamine (CAS 1630850-28-0)
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- 7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine (CAS 1956371-18-8)
- N-(3-Chloro-4-methylphenyl)-2-((5,6-diphenyl-1,2,4-triazin-3-yl)thio)acetamide (CAS 333328-32-8)
- 1,4-Bis(2-chloro-1,1,1,3,3,3-hexafluoropropan-2-yl)benzene (CAS 667938-77-4)
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- 2-Chloro-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzenesulfonamide (CAS 866018-72-6)
Recommended Standards
- 5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole (CAS 188539-59-5)
- Tert-butyl (2,6-diiodopyridin-3-yl) carbonate (CAS 1138444-12-8)
- Benzobicyclon (CAS 156963-66-5)
- 0615AD 1186311-08-9 C10H11I2NO3 tert-Butyl 3,5-diiodopyridin-4-yl carbonate (CAS 1186311-08-9)
- 2-(4-Fluorophenyl)-5-methyl-1,3,4-oxadiazole (CAS 145694-80-0)
- MEthyl 4-(6-methoxy-3-pyridinyl)benzoate (CAS 406234-25-1)
- 2-(4-(4-Methoxyphenyl)piperazin-1-yl)-5-nitrobenzonitrile (CAS 451459-93-1)
- 2-(Isoquinolin-4-yl)acetonitrile (CAS 111164-76-2)
- tert-Butyl 5-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 397864-14-1)
- N,N'-(9,10-dioxo-9,10-dihydroanthracene-1,4-diyl)bis(2,2,2-trifluoroacetamide) (CAS 341966-12-9)
- (Octahydro-9aH-quinolizin-9a-yl)methanol (CAS 25516-32-9)
- 1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid (CAS 1198436-63-3)
- 3-(4-Nitrophenyl)-1-phenylprop-2-yn-1-one (CAS 39833-49-3)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com