1,4-Bis(2-chloro-1,1,1,3,3,3-hexafluoropropan-2-yl)benzene CAS 667938-77-4

Description

The molecular framework of 1,4-Bis(2-chloro-1,1,1,3,3,3-hexafluoropropan-2-yl)benzene (C12H4Cl2F12) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

1,4-Bis(2-chloro-1,1,1,3,3,3-hexafluoropropan-2-yl)benzene (CAS 667938-77-4) is a high-purity analytical reference standard with the molecular formula C12H4Cl2F12 and a molecular weight of 447.05 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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