Adrenaline EP Impurity F CAS 78995-75-2
| CAS No. | 78995-75-2 |
| Molecular Formula | C9H13NO5S |
| Molecular Weight | 247.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Adrenaline EP Impurity F (CAS 78995-75-2, C9H13NO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Adrenaline EP Impurity F (C9H13NO5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Adrenaline EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13NO5S |
| Molecular Weight | 247.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Adrenaline Standards
- Rac-Adrenaline EP Impurity F (Epinephrine Sulfonic Acid) (CAS 26405-77-6)
- Adrenaline Impurity 27 (CAS CATO-C4X-184927)
- Adrenaline Impurity 28 (CAS CATO-C4X-184928)
- Adrenaline Impurity 88 (CAS 139183-81-6)
- Adrenaline Impurity 93 (CAS CATO-C4X-184993)
- Adrenaline Impurity 95 (CAS 2972574-99-3)
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- Adrenaline Impurity 34 (CAS 1095714-91-2)
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