Spironolactone EP Impurity C CAS 976-70-5
| CAS No. | 976-70-5 |
| Molecular Formula | C22H30O3 |
| Molecular Weight | 342.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Spironolactone EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Spironolactone EP Impurity C (CAS 976-70-5, C22H30O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Spironolactone EP Impurity C (C22H30O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H30O3 |
| Molecular Weight | 342.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Spironolactone Standards
- Spironolactone Impurity 16 (CAS CATO-C4X-134516)
- Spironolactone EP Impurity F (CAS 976-71-6)
- Spironolactone Impurity 19 (CAS CATO-C4X-134519)
- Spironolactone Impurity 17 (CAS CATO-C4X-134517)
- Spironolactone Impurity 10 (CAS 53866-23-2)
- Spironolactone Impurity 12 (CAS CATO-C4X-134512)
- Spironolactone Gammalactone Impurity (CAS 20802-57-7)
- Spironolactone Impurity 15 (CAS CATO-C4X-134515)
Recommended Standards
- Dodecanoylalanylalanine (CAS CATO-C3D-263159)
- Megestrol Acetate EP Impurity B (CAS 3562-63-8)
- Testosterone Propionate EP Impurity D (CAS 977-32-2)
- Medroxyprogesterone impurity 10 (CAS 15399-87-8)
- Valsartan Impurity 82 (CAS 1189547-11-2)
- Azelastine Impurity 50 (CAS CATO-C4X-139650)
- Glycyrrhizic Acid Impurity 26 (CAS CATO-C4X-253726)
- 3-(5-Chloro-4-fluoropyridin-3-yl)propan-1-amine (CAS 1393538-95-8)
- tert-Butyl N-[(pyrrolidin-3-yl)methyl]carbamate hydrochloride (CAS 1188263-69-5)
- 4-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 2095797-20-7)
- 3,5-Dihydroxy-4-isopropylbenzoic acid (CAS 1213826-92-6)
- (1-Methyl-2-trifluoromethoxy-ethyl)-carbamic acid benzyl ester (CAS 1208080-26-5)
- 3-Fluoro-6-(trifluoromethoxy)picolinic acid (CAS 1804587-45-8)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com