Indometacin Impurity 55 CAS CATO-C4X-147055
| CAS No. | CATO-C4X-147055 |
| Molecular Formula | C19H15Cl2NO4 |
| Molecular Weight | 392.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Indometacin Impurity 55 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Indometacin Impurity 55 (CAS CATO-C4X-147055, C19H15Cl2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Indometacin Impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl2NO4 |
| Molecular Weight | 392.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indometacin Standards
- Indometacin EP Impurity G (CAS 402849-26-7)
- Indometacin EP Impurity I (CAS 16401-99-3)
- Indometacin EP Impurity H (CAS 1601-18-9)
- Indometacin EP Impurity F (CAS 402849-27-8)
- Indometacin Impurity 19 (CAS CATO-C4X-147019)
- Indometacin Impurity 22 (CAS 78458-34-1)
- Indometacin Impurity 23 (CAS CATO-C4X-147023)
- Indometacin Impurity 31 (CAS CATO-C4X-147031)
Recommended Standards
- tributyl-(5-methylthiazol-2-yl)stannane (CAS 848613-91-2)
- Methyl 1-(2-(2,4-dichlorophenoxy)propanoyl)-1H-indole-3-carboxylate (CAS 431909-77-2)
- Lifitegrast Impurity 171 (CAS CATO-C4X-2409171)
- Ethyl 2-(5-(4-chlorophenoxy)-2-(4-chlorophenyl)oxazol-4-yl)acetate (CAS 68430-59-1)
- Nimodipine Impurity 4 (CAS CATO-C4X-13854)
- Olmesartan Impurity 47 (CAS 1048948-15-7)
- Treprostinil Impurity 13 (CAS CATO-C4X-211613)
- 2-Oxepanone, polymer with 1,2-ethanediamine and 1,1'-methylenebis[4-isocyanatocyclohexane] (CAS 50821-47-1)
- Phenazine methosulfate (CAS 299-11-6)
- Ciprofloxacin impurity 47 (CAS 93106-58-2（free base）)
- 2,3,4,5-Benzazepin-2-one 7-oxoacetic Acid (CAS 1094543-96-0)
- Ethyl 4-butoxy-5-fluoro-2,6-dioxohexahydropyrimidine-5-carboxylate (CAS 65906-75-4)
- Diethyl 3,5-Pyridinedicarboxylate (CAS 4591-56-4)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com