Atenolol EP Impurity J CAS 81346-71-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.81346-71-6
Molecular FormulaC11H16N2O3
Molecular Weight224.26 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Atenolol EP Impurity J CAS 81346-71-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 224.26 g/mol gives Atenolol EP Impurity J distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Atenolol EP Impurity J (CAS 81346-71-6) is a certified pharmaceutical impurity reference standard with the molecular formula C11H16N2O3 and a molecular weight of 224.26 g/mol.

The molecular framework of Atenolol EP Impurity J (C11H16N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Atenolol EP Impurity J under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H16N2O3
Molecular Weight224.26 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Nitrogen Atoms2

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