Metronidazole Impurity 30 CAS 13182-90-6
| CAS No. | 13182-90-6 |
| Molecular Formula | C13H12ClN3O4 |
| Molecular Weight | 309.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Metronidazole Impurity 30 (CAS 13182-90-6, C13H12ClN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Metronidazole Impurity 30 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Metronidazole Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12ClN3O4 |
| Molecular Weight | 309.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Metronidazole Standards
- Metronidazole Impurity 28 (CAS 102274-41-9)
- Metronidazole Impurity 29 (CAS 102274-40-8)
- Metronidazole Impurity 27 (CAS CATO-C4X-140527)
- Metronidazole Impurity 9 (CAS 87009-72-1)
- Metronidazole benzoate (CAS 13182-89-3)
- Metronidazole beta-D-Glucuronide (CAS 100495-98-5)
- Metronidazole Impurity 25 (CAS 16156-93-7)
- Metronidazole Impurity 20 (CAS 19765-12-9)
Recommended Standards
- Resmetirom impurity 93 (CAS CATO-C4X-291293)
- 5-[(4-chlorophenyl)sulfanyl]-2-nitrobenzoic acid (CAS 1036467-51-2)
- Avanafil Impurity 42 (CAS CATO-C4X-111842)
- 2-(((5-Chlorobenzo[d]oxazol-2-yl)thio)methyl)-5-hydroxy-4H-pyran-4-one (CAS 1424561-67-0)
- Ezetimibe Impurity 70 (CAS 937636-63-0)
- Finerenone Impurity 30 (CAS 1891930-37-2)
- Dexamethasone Impurity 23 (CAS 59860-99-0)
- 17B(H),21a(H)-(22RS)-Homohopane (CAS 54352-49-7)
- Timolol Maleate (CAS 26921-17-5)
- 1-bromo-4-(oxan-2-yl)butan-2-one (CAS 1515456-13-9)
- 1-N-Isopropyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1,2-diamine (CAS 2096998-67-1)
- N/A (CAS CATO-CQCM100830)
- [2-fluoro-1-(fluoromethyl)ethyl] trifluoromethanesulfonate (CAS 2098639-00-8)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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