2-Chloro-7-(trifluoromethyl)quinoline CAS 83183-56-6
| CAS No. | 83183-56-6 |
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-7-(trifluoromethyl)quinoline (CAS 83183-56-6), a certified reference material (molecular formula C10H5ClF3N, MW 231.60 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2-Chloro-7-(trifluoromethyl)quinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-7-(trifluoromethyl)quinoline (CAS 104612-21-7)
- 6-Chloro-8-(trifluoromethyl)quinoline (CAS 1065074-68-1)
- 1-chloro-6-(trifluoromethyl)isoquinoline (CAS 1196152-92-7)
- 1-Chloro-7-(trifluoromethyl)isoquinoline (CAS 1196154-02-5)
- 4-Chloro-3-nitrotrifluorotoluene (CAS 121-17-5)
- 8-Chloro-6-(trifluoromethyl)quinoline (CAS 1215206-39-5)
- 1-Chloro-8-trifluoromethyl-isoquinoline (CAS 1283719-92-5)
- 3-Chloro-6-(trifluoromethyl)isoquinoline (CAS 1357945-78-8)
Recommended Standards
- 2-Chloro-4-(trifluoromethyl)quinoline (CAS 2806-29-3)
- 2-Chloro-8-(trifluoromethyl)quinoline (CAS 920494-31-1)
- 2-Chloro-3-(trifluoromethyl)quinoline (CAS 25199-86-4)
- 4-Chloro-6-(trifluoromethyl)quinoline (CAS 49713-56-6)
- (R)-2-(3-Fluorophenyl)oxirane (CAS 403501-35-9)
- Bis[9,9-dimethyl-2-(2-quinolinyl-κN)-9H-fluoren-3-yl-κC](2,4-pentanedionato-κO2,κO4)iridium (CAS 889750-25-8)
- 6-Cyclohexyloxy-2-fluoropyridine-3-boronic acid (CAS 2096332-44-2)
- (3R)-1-Methyl-3-Pyrrolidinemethanol (CAS 1210935-33-3)
- 2-Chlorobenzene-1,3,5-triol (CAS 84743-76-0)
- 2-(Bromomethyl)-3,6-dimethylpyridine (CAS 119292-07-8)
- Fezolinetant Impurity 17 (CAS CATO-C4X-327017)
- (4-(Difluoromethyl)-5-iodopyridin-3-yl)methanol (CAS 1805320-33-5)
- 1-cyclobutyl-1-(4-methoxyphenyl)methanamine hydrochloride (CAS 1864074-74-7)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com