Hydrocortisone Impurity 38 CAS 83196-56-9
| CAS No. | 83196-56-9 |
| Molecular Formula | C20H25NO2 |
| Molecular Weight | 311.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Hydrocortisone Impurity 38 (CAS 83196-56-9, C20H25NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Hydrocortisone Impurity 38 (C20H25NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 311.42 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Hydrocortisone Impurity 38 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H25NO2 |
| Molecular Weight | 311.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 1 |
Related Hydrocortisone Standards
- Hydrocortisone Impurity 17 (CAS 21590-20-5)
- Hydrocortisone Impurity (CAS 20287-97-2)
- Hydrocortisone Impurity 31 (CAS 10184-70-0)
- Hydrocortisone (E)-17-Deoxyaldehyde Derivative (CAS 105562-12-7)
- Hydrocortisone (Z)-17-Deoxyaldehyde Derivative (CAS 105562-13-8)
- Hydrocortisone Impurity 68 (CAS 3103-16-0)
- Hydrocortisone EP Impurity L (CAS 641-77-0)
- Hydrocortisone EP Impurity F (CAS 152-58-9)
Recommended Standards
- Tamoxifen EP Impurity G (CAS 68047-07-4)
- Trihexyphenidyl Impurity 16 (CAS 2724762-69-8)
- Salbutamol Impurity 132 (CAS CATO-C4X-1176132)
- Dienogest (CAS 65928-58-7)
- Metoprolol Impurity 22 (CAS 123195-72-2)
- Rivaroxaban Impurity 108 (CAS CATO-C4X-1090108)
- Iopromide Impurity 12 (CAS CATO-C4X-183212)
- 3-Fluoro-3-(fluoromethyl)piperidine hydrochloride (CAS 2306271-69-0)
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- trans-4-(Cbz-amino)cyclohexanol (CAS 27489-63-0)
- 5-Amino-1-methyl-3-(2-methylbutyl)pyrimidine-2,4(1h,3h)-dione (CAS 1342574-56-4)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com