Mometasone Furoate EP Impurity A CAS 83880-65-3
| CAS No. | 83880-65-3 |
| Molecular Formula | C27H29ClO5 |
| Molecular Weight | 468.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Mometasone Furoate EP Impurity A (CAS 83880-65-3), a pharmacopoeial impurity reference standard (molecular formula C27H29ClO5, MW 468.97 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H29ClO5, Mometasone Furoate EP Impurity A contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 468.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C27H29ClO5 |
| Molecular Weight | 468.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Impurity C84 (CAS 722495-06-9)
- Mometasone Impurity 49 (CAS CATO-C4X-170449)
- Mometasone Impurity 41 (CAS CATO-C4X-170441)
- Mometasone Furoate EP Impurity C (CAS 1305334-31-9)
- Mometasone Furoate EP Impurity D (CAS 83881-09-8)
- Mometasone Impurity 33 (CAS CATO-C4X-170433)
- Mometasone Furoate EP Impurity O (CAS 24916-91-4)
- Mometasone Furoate EP Impurity N (CAS 352315-75-4)
Recommended Standards
- Brexpiprazole Impurity 92 (CAS CATO-C4X-113192)
- (3-Amino-4-((4-chlorophenyl)sulfonyl)-5-(phenylamino)thiophen-2-yl)(phenyl)methanone (CAS 866844-40-8)
- Brexpiprazole Impurity 90 (CAS CATO-C4X-113190)
- Clobetasol Propionate EP Impurity D (CAS 25120-99-4)
- Benzhexol Impurity 01 (CAS 13150-57-7)
- Sulfadimethoxine Impurity (CAS 80314-58-5)
- Betahistine Impurity 48 (CAS CATO-C4X-183848)
- 4-Methoxy-1-(pyrrolidin-3-yl)-1H-pyrazole (CAS 1850217-39-8)
- tert-Butyl(cyclopent-3-en-1-yloxy)diphenylsilane (CAS 182801-94-1)
- {hexahydrospiro[cyclopropane-1,2'-pyrrolizine]-7'a-yl}methanamine (CAS 1788873-90-4)
- Methyl 3-bromo-2,4,5-trifluorobenzoate (CAS 195532-60-6)
- (1S,2S)-(+)-1,2-Diaminocyclohexane 21436-03-3 (+)-(S,S)-1,2-DIAMINOCYCLOHEXANE;(1S)-(+)-TRANS-1,2-DIAMINOCYCLOHEXANE;(1S)-TRANS-1,2-CYCLOHEXANEDIAMINE;(1S)-TRANS-1,2-DIAMINOCYCLOHEXANE;(1S,2S)-(+)-1,2-CYCLOHEXANEDIAMINE;(1S,2S)-(+)-1,2-DIAMINOCYCLOHEXANE;(1S,2S)-(+)-CYCLOHEXANE-1,2-DIAMINE;(1S,2S)-1,2-CYCLOHEXANEDIAMINE;(1S,2S)-1,2-DIAMINOCYCLOHEXANE;(1S,2S)-CYCLOHEXANE-1,2-DIAMINE;(1S,2S)-DIAMINOCYCLOHEXANE;(S,S)-(+)-1,2-DIAMINOCYCLOHEXANE;(S,S)-1,2-DIAMINOCYCLOHEXANE;(S,S)-DACH;1,2-CYCLOHEXANEDIAMINE, (1S,2S)-;S-CHDA;S-DACH;SS-DAC;SS-DIAMINOCYCLOHEXANE SC11732 (CAS 21436-03-3)
- Di-tert-butyl 1-(4-chlorobenzyl)hydrazine-1,2-dicarboxylate (CAS 1624262-64-1)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com