Bromfenac Impurity 2 CAS 845276-75-7
| CAS No. | 845276-75-7 |
| Molecular Formula | C13H10BrNO |
| Molecular Weight | 276.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bromfenac Impurity 2 (C13H10BrNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Bromfenac Impurity 2 (CAS 845276-75-7), a pharmacopoeial impurity reference standard (molecular formula C13H10BrNO, MW 276.13 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10BrNO |
| Molecular Weight | 276.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromfenac Standards
- Bromfenac Impurity 79 (CAS CATO-C4X-200279)
- Bromfenac Impurity 22 (CAS 61112-01-4)
- Bromfenac Impurity 76 (CAS 1623751-93-8)
- Bromfenac Impurity 72 (CAS 61941-63-7)
- Bromfenac Impurity 13 (CAS CATO-C4X-200213)
- Bromfenac Impurity 31 (CAS 71969-36-3)
- Bromfenac Impurity 26 (CAS 76049-81-5)
- Bromfenac Impurity 52 (CAS CATO-C4X-200252)
Recommended Standards
- 6-bromospiro[2H-benzofuran-3,4'-oxazolidine]-2'-one (CAS 2407719-41-7)
- Cuspin-1 (CAS 337932-29-3)
- 6-Bromo-1-ethylbenzo[cd]indol-2(1H)-one (CAS 41503-32-6)
- Ethyl 2-(3-bromoisoxazol-5-yl)-3-methylbutanoate (CAS 2724270-76-0)
- Benzalkonium Chloride impurity 7 (CAS 14727-68-5)
- Isoflurane EP Impurity D (CAS 32778-07-7)
- Troxerutin Impurity 5 (CAS 125092-04-8)
- 2-Bromo-6-nitropyridine (CAS 21203-78-1)
- (2-Chloro-3-cyano-5-cyclopropylphenyl)boronic acid (CAS 2225172-77-8)
- 6-Chloro-4-(chloromethyl)pyridin-2-amine (CAS 1393566-32-9)
- 4-Methyl-2-pyrrolidin-2-yl-pyrimidine-5-carboxylic acidphenylamide hydrochloride (CAS 1361114-95-5)
- 1-[(4-nitrobenzene)sulfonyl]imidazole (CAS 110349-30-9)
- 4-(Cyanomethyl)-5-(difluoromethyl)-3-fluoropicolinonitrile (CAS 1804491-58-4)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com