Apalutamide Impurity 44 CAS 1121056-94-7
| CAS No. | 1121056-94-7 |
| Molecular Formula | C6H4F3N3O2 |
| Molecular Weight | 207.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apalutamide Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Apalutamide Impurity 44 (CAS 1121056-94-7), a pharmacopoeial impurity reference standard (molecular formula C6H4F3N3O2, MW 207.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Apalutamide Impurity 44 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H4F3N3O2 |
| Molecular Weight | 207.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Apalutamide Standards
- Apalutamide Impurity 64 (CAS 1211542-14-1)
- Apalutamide Impurity 46 (CAS CATO-C4X-274946)
- Apalutamide Impurity 106 (CAS CATO-C4X-2749106)
- Apalutamide Impurity 50 (CAS CATO-C4X-274950)
- Apalutamide Impurity 51 (CAS CATO-C4X-274951)
- Apalutamide Impurity 117 (CAS CATO-C4X-2749117)
- Apalutamide Impurity 60 (CAS CATO-C4X-274960)
- Apalutamide Impurity 61 (CAS 1513077-71-8)
Recommended Standards
- Riluzole impurity 20 (CAS 1644-88-8)
- Riluzole impurity 19 (CAS 2995-45-1)
- 6-Hydroxy-4-(trifluoromethyl)nicotinic acid (CAS 849020-87-7)
- 2-Amino-5-bromo-4,6-dimethylpyridine 2-amino-4,6-dimethyl-5-bromopyridine 2-amino-5-bromo-4 6-dimethylpyridine& 2-amino-5-bromo-4,6-dimethylpyridine 97% 3-bromo-2,4-dimethylpyridin-6-amine 5-bromo-4,6-dimethyl-2-pyridinamine 5-bromo-4,6-dimethyl-2-pyridinamine, 6-amino-3-bromo-2,4-lutidine 5-bromo-4,6-dimethylpyridin-2-amine 6-amino-2,4-dimethyl-3-bromopyridine 6-amino-3-bromo-2,4-iutidine 89856-44-0 (CAS 89856-44-0)
- Ambroxol impurity 116 (CAS 1373889-89-4)
- Estrone impurity 6 (CAS 1089-80-1)
- Ibrutinib Impurity 36 (CAS CATO-C4X-106436)
- 4-(4-Chloro-6-methoxy-2-methyl-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CAS 1627721-80-5)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-4-acetic acid (CAS 1361904-77-9)
- 4,5-Dihydroimidazo[1,5-a]quinoxaline (CAS 512847-94-8)
- N-(4-Bromophenyl)-1-methyl-1H-benzo[d]imidazol-2-amine (CAS 330793-27-6)
- Benzyl (3R,4R)-3-amino-4-fluoropyrrolidine-1-carboxylate (CAS 1776114-11-4)
- 9-(3-(Benzyloxy)benzyl)-2-chloro-N,N-dimethyl-9H-purin-6-amine (CAS 115204-70-1)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com