Thiamine /Vitamin B1 Impurity 55 CAS 855380-68-6
| CAS No. | 855380-68-6 |
| Molecular Formula | C12H17ClN4OS2 |
| Molecular Weight | 332.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Thiamine /Vitamin B1 Impurity 55.
As a process- or degradation-related impurity, Thiamine /Vitamin B1 Impurity 55 (CAS 855380-68-6, C12H17ClN4OS2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, Thiamine /Vitamin B1 Impurity 55 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Thiamine /Vitamin B1 Impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17ClN4OS2 |
| Molecular Weight | 332.87 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Thiamine Standards
- Thiamine /Vitamin B1 Impurity 50 (CAS 10553-88-5)
- Thiamine Impurity 41 (CAS 92325-11-6)
- Thiamine-13C3 Hydrochloride (CAS CATO-C4X-187317)
- Thiamine Nitrate EP Impurity A (CAS 2380-61-2)
- Thiamine /Vitamin B1 Impurity 29 (CAS CATO-C4X-187329)
- Thiamine Impurity 42 (CAS 38655-47-9)
- Thiamine Impurity 32 (CAS 52164-53-1)
- Thiamine /Vitamin B1 Impurity 56 (CAS 1153-39-5)
Recommended Standards
- 4-Chloro-6,7-dihydro-2-[(phenylthio)methyl]-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine (CAS 793727-55-6)
- Venetoclax Impurity 139 (CAS CATO-C4X-2495139)
- tert-Butyl 4-((2-chloro-N-isopropylacetamido)methyl)piperidine-1-carboxylate (CAS 1353988-35-8)
- Vortioxetine Impurity 98 (CAS 1240670-87-4)
- Nitroso Perindopril EP impurity U (CAS CATO-C4X-125258)
- Riboflavin lmpurity 20 (CAS 57609-95-7)
- Ibrutinib Impurity 46 (CAS 330786-24-8)
- Ibuprofen Impurity 103 (CAS CATO-C4X-1082103)
- 2-Chloro-5-(2-(trifluoromethyl)phenyl)isonicotinic acid (CAS 1261680-60-7)
- 1-nitro-4-[2-(4-nitrophenoxy)ethoxy]benzene (CAS 14467-69-7)
- 1-(Bromomethyl)-1-(2-methylbutyl)cyclopentane (CAS 1483205-72-6)
- Thalidomide-O-amido-C6-NH2 (TFA) (CAS 1950635-14-9)
- 2,2,2-Trifluoroethyl (4-(trifluoromethyl)phenyl)carbamate (CAS 23794-80-1)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com