5-((Trimethylsilyl)ethynyl)pyrimidin-2-amine CAS 857265-75-9
| CAS No. | 857265-75-9 |
| Molecular Formula | C9H13N3Si |
| Molecular Weight | 191.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-((Trimethylsilyl)ethynyl)pyrimidin-2-amine (CAS 857265-75-9), a certified reference material (molecular formula C9H13N3Si, MW 191.31 g/mol) for analytical method development and quality control.
The molecular framework of 5-((Trimethylsilyl)ethynyl)pyrimidin-2-amine (C9H13N3Si) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-((Trimethylsilyl)ethynyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13N3Si |
| Molecular Weight | 191.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Trimethylsilyl Standards
- 3-((Trimethylsilyl)ethynyl)pyrazin-2-amine (CAS 1005349-12-1)
- 4-[2-(Trimethylsilyl)ethynyl]pyrimidin-2-amine (CAS 1214264-40-0)
- 5-((Trimethylsilyl)ethynyl)pyridazin-4-amine (CAS 1333319-58-6)
- 1-(Trimethylsilyl)-1H-benzo[d][1,2,3]triazole (CAS 43183-36-4)
- 5-((Trimethylsilyl)ethynyl)pyridin-2(1H)-one (CAS 1064706-78-0)
- 2-(Trimethylsilyl)furo[2,3-b]pyridine (CAS 111079-43-7)
- 2-(Trimethylsilyl)furo[3,2-b]pyridine (CAS 111079-44-8)
- 1171920-09-4 3-((Trimethylsilyl)ethynyl)pyridin-4-ol 9860AC C10H13NOSi (CAS 1171920-09-4)
Recommended Standards
- 4-octylÂpyridine (CAS 40089-91-6)
- 6-(P-tolyl)hexan-1-amine (CAS 51278-34-3)
- 4-Methyl-1-(o-tolyl)pentan-1-amine (CAS 854185-22-1)
- ALYSSIN (CAS 646-23-1)
- 2-(Methoxymethyl)pyridin-3-ol (CAS 188670-04-4)
- 2-{2-[(4-phenoxyphenyl)amino]-1,3-thiazol-4-yl}acetic acid (CAS 927983-71-9)
- 2'-Methyl-5'-(trifluoromethyl)spiro[cyclohexane-1,1'-isoindoline]-3',4-dione (CAS 2377418-05-6)
- 6,8-Dibromo-3-(4-methylbenzenesulfonyl)quinolin-2-amine (CAS 866019-18-3)
- 4-(2-Chloro-4-methoxyphenyl)-2-morpholino-5-(4H-1,2,4-triazol-3-yl)thiophene-3-carbonitrile (CAS 1202041-57-3)
- 1-(2-Hydroxyhexyl)-1-methyl-4-phenylpiperidin-1-ium iodide (CAS 1078611-26-3)
- 4-Nitro-Z-Gly-Trp-Gly-OH (M-1595.0050) (CAS 64792-79-6)
- 4-(Chloromethoxy)-1,2-difluorobenzene (CAS 1521891-48-4)
- (3Z)-1-(4-Chlorophenyl)-3-[(dimethylamino)methylidene]pyrrolidin-2-one (CAS 339020-56-3)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
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