Tranexamic Acid Impurity 13 CAS 85888-81-9
| CAS No. | 85888-81-9 |
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tranexamic Acid Impurity 13 (CAS 85888-81-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClO2 and a molecular weight of 170.59 g/mol.
Structurally, Tranexamic Acid Impurity 13 (C8H7ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 170.59 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tranexamic Acid Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
Related Tranexamic Standards
- Tranexamic Acid Impurity 12 (CAS 31719-77-4)
- Tranexamic Impurity 16 (CAS 1642-81-5)
- Tranexamic Impurity 18 (CAS 2375016-71-8)
- Tranexamic Impurity 24 (CAS CATO-C4X-177124)
- Tranexamic Acid-13C2,15N (CAS 1292837-95-6)
- Tranexamic-d2 Acid (CAS 2714435-89-7)
- Tranexamic Acid (CAS 1197-18-8)
- Tranexamic Acid EP Impurity B (CAS 1197-17-7)
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- Dacomitinib Impurity 37 (CAS CATO-C4X-208637)
- Pirfenidone Impurity 39 (CAS 51566-22-4)
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