Tranexamic Impurity 18 CAS 2375016-71-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2375016-71-8
Molecular FormulaC8H13ClO2
Molecular Weight176.64 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tranexamic Impurity 18 CAS 2375016-71-8 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Tranexamic Impurity 18 (CAS 2375016-71-8), a pharmacopoeial impurity reference standard (molecular formula C8H13ClO2, MW 176.64 g/mol) used for the identification and quantification of trace impurities in APIs.

Tranexamic Impurity 18 (C8H13ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H13ClO2
Molecular Weight176.64 g/mol
Purity>95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1999
Halogen ContentCl-containing

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