Fluralaner Impurity N3 CAS 864725-61-1
| CAS No. | 864725-61-1 |
| Molecular Formula | C20H16Cl2F3NO3 |
| Molecular Weight | 446.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Fluralaner Impurity N3 (CAS 864725-61-1, C20H16Cl2F3NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fluralaner Impurity N3 (C20H16Cl2F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 446.25 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluralaner Impurity N3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16Cl2F3NO3 |
| Molecular Weight | 446.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Fluralaner Standards
- Fluralaner Impurity 53 (CAS CATO-C4X-218053)
- Fluralaner Impurity 50 (CAS 1309959-46-3)
- Fluralaner Impurity 23 (CAS CATO-C4X-218023)
- Fluralaner impurity 35 (CAS CATO-C4X-218035)
- Fluralaner impurity 36 (CAS CATO-C4X-218036)
- Fluralaner impurity 41 (CAS CATO-C4X-218041)
- Fluralaner impurity 32 (CAS CATO-C4X-218032)
- Fluralaner impurity 43 (CAS CATO-C4X-218043)
Recommended Standards
- Citicoline Impurity 8 (CAS 3036-18-8)
- Cytidine Diphosphate Ethanolamine (CDPEA) (CAS 3038-18-8)
- N,N'-(Ethane-1,2-diyl)bis(3-chloropropanamide) (CAS 31481-06-8)
- tert-Butyl N-[(E)-3-tributylstannylallyl]carbamate (CAS 139111-44-7)
- Nefopam Impurity 37 (CAS CATO-C4X-283737)
- Brexpiprazole Impurity 19 (CAS 23967-57-9)
- Brexpiprazole Impurity N19 (CAS 2059942-14-0)
- (2S,3R)-2-Amino-4,4-difluoro-3-hydroxybutanoic acid (CAS 438477-05-5)
- Copper(II) 11-methyldodecanoate (CAS 93963-85-0)
- 5-Fluoroindoline-2-carboxamide (CAS 422572-51-8)
- (E)-3-(2,3-dimethylphenyl)acrylic acid (CAS 361483-09-2)
- 5-Methyl-4-(methylamino)pyrimidin-2-ol (CAS 62006-34-2)
- N-(2-Oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl)methanesulfonamide (CAS 898426-64-7)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com