Irinotecan Impurity 40 CAS 86639-51-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.86639-51-2
Molecular FormulaC22H20N2O5
Molecular Weight392.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Irinotecan Impurity 40 CAS 86639-51-2 chemical structure

Description

CATO manufactures Irinotecan Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Irinotecan Impurity 40 (CAS 86639-51-2) is a certified pharmaceutical impurity reference standard with the molecular formula C22H20N2O5 and a molecular weight of 392.40 g/mol.

Irinotecan Impurity 40 (C22H20N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC22H20N2O5
Molecular Weight392.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Nitrogen Atoms2

Related Irinotecan Standards

Recommended Standards

Why CATO?