Nintedanib Impurity 129 CAS CATO-C4X-1814129
| CAS No. | CATO-C4X-1814129 |
| Molecular Formula | C16H24N4O3 |
| Molecular Weight | 320.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nintedanib Impurity 129.
Nintedanib Impurity 129 (CAS CATO-C4X-1814129) is a certified pharmaceutical impurity reference standard with the molecular formula C16H24N4O3 and a molecular weight of 320.39 g/mol.
Structurally, Nintedanib Impurity 129 (C16H24N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 320.39 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nintedanib Impurity 129 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24N4O3 |
| Molecular Weight | 320.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nintedanib Standards
- Nintedanib Impurity 146 (CAS CATO-C4X-1814146)
- Nintedanib Impurity 147 (CAS CATO-C4X-1814147)
- Nintedanib Impurity 149 (CAS CATO-C4X-1814149)
- Nintedanib Impurity 85 (CAS CATO-C4X-181485)
- Nintedanib Impurity 122 (CAS CATO-C4X-1814122)
- Nintedanib Impurity 89 (CAS CATO-C4X-181489)
- Nintedanib Impurity 154 (CAS CATO-C4X-1814154)
- Nintedanib Impurity 158 (CAS 1023942-14-4)
Recommended Standards
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- Niraparib R-enantiomer p-tosylate (CAS 1038915-58-0)
- Cabazitaxel Impurity N4 (CAS 1262147-55-6)
- Upadacitinib Impurity 3 (CAS CATO-C4X-24053)
- Dexamethasone Impurity 113 (CAS CATO-C4X-1165113)
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- 3-(2,3-dihydro-1-benzofuran-5-yl)aniline (CAS 893637-27-9)
- 3-Aminooxetane-2-carboxylic acid (CAS 1427385-82-7)
- 7,8-Dimethyl-1,7-dihydro-6H-purin-6-one (CAS 58192-87-3)
- Ofloxacin EP Impurity E(HCl) (CAS 402930-70-5)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com