Ivacaftor Impurity 4 CAS 873055-55-1
| CAS No. | 873055-55-1 |
| Molecular Formula | C16H23NO5 |
| Molecular Weight | 309.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ivacaftor Impurity 4 (C16H23NO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ivacaftor Impurity 4 (CAS 873055-55-1) is a certified pharmaceutical impurity reference standard with the molecular formula C16H23NO5 and a molecular weight of 309.36 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ivacaftor Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H23NO5 |
| Molecular Weight | 309.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Ivacaftor Standards
Recommended Standards
- Tegoprazan Impurity 139 (CAS CATO-C4X-2297139)
- Dimefline Impurity 10 (CAS 95279-60-0)
- Tegoprazan Impurity 12 (CAS 1640981-20-9)
- tert-butyl (R)-(3-(benzyloxy)-1-hydrazinyl-1-oxopropan-2-yl)carbamate (CAS 295338-04-4)
- Mirogabalin Impurity 215 (CAS CATO-C4X-2924215)
- Alprostadil EP Impurity K (CAS 791-28-6)
- Etodolac EP Impurity E (CAS 57817-27-3)
- 1,5-Diamino-2,4,6,8-tetrachloroanthracene-9,10-dione (CAS 83578-91-0)
- 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-galactopyranose (CAS 155488-15-6)
- Alternariol-d2 (CAS CATO-CCAD302675)
- Ethyl 6-amino-2-(((6-(tert-butyl)-3-cyano-4-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)methyl)-5-cyano-4-(thiophen-2-yl)-4H-pyran-3-carboxylate (CAS 497230-56-5)
- 3-Ethyl-2-propylquinoline-4-carboxylic acid (CAS 380346-48-5)
- 2-[4-Chloro-3-(trifluoromethyl)benzenesulfonamido]-4-(methylsulfanyl)butanoic acid (CAS 1009232-49-8)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com