Nebivolol USP Related Compound C CAS 876514-31-7
| CAS No. | 876514-31-7 |
| Molecular Formula | 2*C11H11FO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 194.20 g/mol gives Nebivolol USP Related Compound C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nebivolol USP Related Compound C (CAS 876514-31-7), molecular formula C11H11FO2 and molecular weight 194.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Nebivolol USP Related Compound C is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 194.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C11H11FO2 |
| Molecular Weight | 194.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Nebivolol Standards
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 20 (CAS 105300-40-1)
- Nebivolol Impurity 28 (CAS 112068-01-6)
- D-Nebivolol (SR,RR) (CAS 118457-15-1)
- L-Nebivolol (RS,SS) (CAS 118457-16-2)
- Nebivolol Hydrochloride EP Impurity B (CAS 119365-23-0)
- Nebivolol Impurity 32（SS,RS）or（SR,SS） (CAS 119365-25-2)
Recommended Standards
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- Cyclopenta[kl]acridine (CAS 31332-53-3)
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- 6-Chloro-5-fluoro-3-iodopyridin-2-amine (CAS 2734861-54-0)
- n1,n1-Diisopropyl-n2-(1-methoxypropan-2-yl)ethane-1,2-diamine (CAS 1250429-36-7)
- Isoquinoline-7,8-diamine (CAS 120546-60-3)
- Ethyl 5-cyclohexyl-1,2,4-oxadiazole-3-carboxylate (CAS 1343186-43-5)
- 5-Bromo-2-ethylbenzofuran (CAS 39178-60-4)
- Tert-butyl (1-(3-aminopyridin-2-yl)piperidin-4-yl)carbamate (CAS 1023655-15-3)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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