5-[4-(Trifluoromethyl)phenyl]-2-piperidone CAS 87922-74-5
| CAS No. | 87922-74-5 |
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-[4-(Trifluoromethyl)phenyl]-2-piperidone (C12H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-[4-(Trifluoromethyl)phenyl]-2-piperidone (CAS 87922-74-5) is a high-purity analytical reference standard with the molecular formula C12H12F3NO and a molecular weight of 243.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-[4-(Trifluoromethyl)phenyl]-2-piperidone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 5-(Trifluoromethyl)-2H-spiro[benzofuran-3,3'-pyrrolidine] (CAS 1047657-74-8)
- 5-(2-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1303743-39-6)
- 5-(3-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1307520-98-4)
- 3-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1350989-17-1)
- 1-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1353087-69-0)
- 1-(3-(Trifluoromethyl)phenyl)piperidin-4-one (CAS 147378-74-3)
- 4-Methyl-4-(3-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1488856-28-5)
- 4-Methyl-4-(4-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1494528-00-5)
Recommended Standards
- 5-(Benzofuran-2-yl)isoxazole-3-carbohydrazide (CAS 5784-29-2)
- 5-Amino-4-cyano-3-methyl-1-(4-nitrophenyl)pyrazole (CAS 76982-31-5)
- 5-(3-Amino-1H-indazol-6-yl)furan-2-carboxylic acid (CAS 871709-81-8)
- 5-Hydroxy-2-deoxycytidine (CAS 52278-77-0)
- 2,4,6-Trimethylbenzoic Acid (CAS 480-63-7)
- Methyl 2-(4-(2-oxopropyl)phenoxy)acetate (CAS 78069-08-6)
- (4-Aminopiperidin-1-yl)(1-(3-fluorophenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 1351843-00-9)
- methyl 2-methyl-4-{[(3-methyloxetan-3-yl)methyl]amino}but-2-enoate (CAS 1704309-15-8)
- 4-Bromo-1-(4-fluorophenyl)butan-1-one (CAS 40132-01-2)
- 2-(2-Fluoro-3-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214323-18-8)
- Z-Arg-Arg-AMC (I-1135.0050) (CAS 88937-61-5)
- 1-Butyl-3-methyl-1H-imidazol-3-ium methyl carbonate (CAS 916850-37-8)
- 3,4-Difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 2244893-49-8)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com