Trimetazidine Impurity 10 HCl CAS 879646-17-0
| CAS No. | 879646-17-0 |
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Trimetazidine Impurity 10 HCl (CAS 879646-17-0), a pharmacopoeial impurity reference standard (molecular formula C15H22N2O4HCl, MW 330.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Trimetazidine Impurity 10 HCl (C15H22N2O4HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22N2O4 HCl |
| Molecular Weight | 330.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimetazidine Standards
- Trimetazidine EP Impurity A DiHCl (CAS 107049-57-0)
- Trimetazidine EP Impurity G (CAS 110-85-0)
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine EP Impurity F（Dihydrochloride） (CAS 113698-83-2)
- Trimetazidine-D8 Dihydrochloride (CAS 1219795-37-5)
- Trimetazidine-d8 Dihydrochloride (CAS 1219908-67-4)
- Trimetazidine EP Impurity B (CAS 1257-19-8)
- Trimetazidine Dihydrochloride (CAS 13171-25-0)
Recommended Standards
- Coumarin Impurity 4 (CAS 2445-80-9)
- Procaterol Impurity 40 (CAS 63483-95-4)
- Fluorescein impurity 01 (CAS 76579-17-4)
- 4-(4-Ethoxyphenyl)-3H-1,2,4-triazole-3,5(4H)-dione (CAS 96567-02-1)
- 3,4-Bis(dimethylamino)phenol (CAS 1243461-55-3)
- 1-Benzhydryl-3-chloroazetidine (CAS 959256-87-2)
- 3-Fluoropyridin-4(1H)-one hydrochloride (CAS 1309602-71-8)
- 4-Amino-2-(3-hydroxypropyl)isoxazolidin-3-one (CAS 755750-44-8)
- (Z)-4-(methylamino)-4-oxobut-2-enoic acid (CAS 6936-48-7)
- Peptide Impurity (CAS CATO-CPTD788810)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com