Riluzole Impurity 1 CAS 88149-49-9
| CAS No. | 88149-49-9 |
| Molecular Formula | C7H4Br2F3NO |
| Molecular Weight | 334.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Riluzole Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Riluzole Impurity 1 (CAS 88149-49-9) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4Br2F3NO and a molecular weight of 334.92 g/mol.
Riluzole Impurity 1 (C7H4Br2F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H4Br2F3NO |
| Molecular Weight | 334.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Riluzole Standards
- Riluzole Impurity 22 (CAS CATO-C4X-200922)
- Riluzole Impurity 4 (CAS 144631-82-3)
- Riluzole Impurity 14 (CAS CATO-C4X-200914)
- Riluzole Impurity 12 (CAS CATO-C4X-200912)
- Riluzole Impurity 7 (CAS 1456696-94-8)
- Riluzole Impurity 25 (CAS 442665-84-1)
- Riluzole Impurity 27 (CAS 2273706-77-5)
- Riluzole Impurity 26 (CAS CATO-C4X-200926)
Recommended Standards
- 6-chloro-4-(nonan-5-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2-ol (CAS CATO-C3D-262396)
- 1,1,1,3,8,9-Hexachlorononane (CAS 865306-21-4)
- 2,5-Dibromo-4-(trifluoromethoxy)aniline (CAS 84483-32-9)
- 6-Bromo-2-iodoquinoxaline (CAS 1083181-44-5)
- Etrasimod Impurity 64 (CAS CATO-C4X-321464)
- Hydrocortisone EP Impurity N (CAS CATO-C4X-140114)
- Macitentan Impurity 24 (CAS 556797-16-1)
- 2-(4-(Difluoromethyl)-2,5-diiodopyridin-3-yl)acetonitrile (CAS 1806032-61-0)
- 3-bromo-1-methyl-1H-indazol-7-amine (CAS 885271-76-1)
- (S)-2-(3-bromobenzyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1260588-94-0)
- Methyl 4-Amino-3-hydroxyphenylacetate (CAS 353525-11-8)
- 2-Ethoxybenzimidazole (CAS 22219-23-4)
- 8-(Trifluoromethyl)quinoline-6-carboxylic acid (CAS 2102411-83-4)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com