Osimertinib Impurity 110 CAS CATO-C4X-2045110
| CAS No. | CATO-C4X-2045110 |
| Molecular Formula | C56H67N14O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Osimertinib Impurity 110 (C56H67N14O4C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Osimertinib Impurity 110 (CAS CATO-C4X-2045110) is a certified pharmaceutical impurity reference standard with the molecular formula C56H67N14O4C2HF3O2 and a molecular weight of 1114.27 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Osimertinib Impurity 110 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C56H67N14O4 2*C2HF3O2 |
| Molecular Weight | 1114.27 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 30.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 14 |
Related Osimertinib Standards
- Osimertinib Impurity 5 (CAS 1009298-59-2)
- Osimertinib Impurity 8 (CAS 1421372-66-8)
- Osimertinib Impurity N1 (CAS 1421372-67-9)
- Osimertinib Impurity N2 (CAS 1421373-36-5 (free base))
- Osimertinib (CAS 1421373-65-0)
- Osimertinib Impurity 10 (CAS 1421373-98-9)
- Osimertinib Impurity N3 (CAS 1421373-99-0)
- Osimertinib-3 (CAS 1446700-26-0)
Recommended Standards
- Doxofylline Impurity 34 (CAS CATO-C4X-151334)
- Diprophylline Impurity 2 (CAS CATO-C4X-26492)
- Cinacalcet Impurity 61 (CAS CATO-C4X-105961)
- 3-(2,2-Dichlorovinyl)-N-(4-iodophenyl)-2,2-dimethylcyclopropane-1-carboxamide (CAS 301359-13-7)
- 1-Methyl-N-phenylhydrazine-1-carbothioamide (CAS 21076-09-5)
- Tert-butyln-[(3S)-6-bromo-2,3-dihydrobenzofuran-3-yl]carbamate (CAS 2364561-61-3)
- tert-Butyl N-(4,4-difluoropyrrolidin-3-yl)carbamate (CAS 1434141-95-3)
- 4-Amino-5-chloro-8-methoxyquinoline-3-carbohydrazide (CAS 1315374-21-0)
- 5-(Adamantan-1-yl)-3-(trifluoromethyl)-1h-pyrazole (CAS 1046463-05-1)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com