Eltrombopag Impurity 37 CAS 7693-52-9
| CAS No. | 7693-52-9 |
| Molecular Formula | C6H4BrNO3 |
| Molecular Weight | 218.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Eltrombopag Impurity 37 (C6H4BrNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Eltrombopag Impurity 37 (CAS 7693-52-9, C6H4BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Eltrombopag Impurity 37 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BrNO3 |
| Molecular Weight | 218.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 34 (CAS 13073-25-1)
- Eltrombopag Impurity 30 (CAS CATO-C4X-119830)
- Eltrombopag Impurity 31 (CAS 4291-30-9)
- Eltrombopag Impurity 43 (CAS 223127-00-2)
- Eltrombopag Impurity 57 (CAS 893736-72-6)
- Eltrombopag Impurity 30 (CAS 168618-47-1)
- Eltrombopag impurity 144 (CAS CATO-C4X-1198144)
- Eltrombopag Impurity 154 (CAS CATO-C4X-1198154)
Recommended Standards
- Clofarabine Impurity 11 (CAS CATO-C4X-159311)
- 2,6-dichloro-7-nitroso-7H-purine (CAS CATO-C3D-26198)
- 2-Bromo-4-nitrophenol (CAS 5847-59-6)
- 2,6-Dichloro-8-Nitroso-7H-Purine (CAS CATO-C3D-26176)
- All-rac-alfa-Tocopherol EP Impurity D (CAS CATO-C4X-119528)
- Ziprasidone Impurity 27 (CAS CATO-C4X-124027)
- Ursodeoxycholic Acid Impurity 110 (CAS CATO-C4X-1422110)
- Sufosfamide (CAS 37753-10-9)
- Diethyl 2-(((4-iodo-2-methylphenyl)-amino)methylene)malonate (CAS 951006-38-5)
- 2-Bromo-3-chloro-5-fluorobenzoic acid (CAS 1525442-25-4)
- 3-Fluorobenzyl chloride (CAS 456-42-8)
- 2,2-Dichloro-1-(4-phenoxyphenyl)ethan-1-one (CAS 59867-68-4)
- methyl 2-[(1-methoxy-1-oxopropan-2-yl)amino]-3-nitrobenzoate (CAS 1644599-14-3)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com