Eltrombopag Impurity 31 CAS 4291-30-9
| CAS No. | 4291-30-9 |
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Eltrombopag Impurity 31 (CAS 4291-30-9), molecular formula C12H9NO3 and molecular weight 215.20 g/mol, is a CATO reference standard with documented purity and traceability.
Eltrombopag Impurity 31 (C12H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 43 (CAS 223127-00-2)
- Eltrombopag Impurity 57 (CAS 893736-72-6)
- Eltrombopag Impurity 30 (CAS CATO-C4X-119830)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
- Eltrombopag Impurity 37 (CAS 7693-52-9)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag Impurity 119 (CAS CATO-C4X-1198119)
- Eltrombopag Impurity 123 (CAS CATO-C4X-1198123)
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