Opicapone Impurity 4 CAS 893767-99-2
| CAS No. | 893767-99-2 |
| Molecular Formula | C8H8ClN3O |
| Molecular Weight | 197.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Opicapone Impurity 4 (CAS 893767-99-2) is a certified pharmaceutical impurity reference standard with the molecular formula C8H8ClN3O and a molecular weight of 197.62 g/mol.
Based on its molecular formula C8H8ClN3O, Opicapone Impurity 4 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 197.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Opicapone Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3O |
| Molecular Weight | 197.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Opicapone Standards
- Opicapone impurity 26 (CAS CATO-C4X-240426)
- Opicapone impurity 69 (CAS CATO-C4X-240469)
- Opicapone Impurity 54 (CAS CATO-C4X-240454)
- Opicapone lmpurity 18 (CAS CATO-C4X-240418)
- Opicapone Impurity 75 (CAS >95%)
- Opicapone Impurity 44 (CAS CATO-C4X-240444)
- Opicapone impurity 21 (CAS 1962082-05-8)
- Opicapone impurity 66 (CAS 1639373-19-5)
Recommended Standards
- Suvorexant Impurity 32 (CAS 32850-82-1)
- Belinostat Impurity 5 (CAS CATO-C4X-34905)
- N-(4-chlorophenyl)-2-oxopropanamide (CAS 52181-18-7)
- Etizolam Impurity 13 (CAS 247188-22-3)
- Metoclopramide Impurity 11 (CAS 111049-74-2)
- Beraprost Impurity 6 (Mixture of Diastereomers) (CAS CATO-C4X-21846)
- Alectinib Impurity N2 (CAS 1256584-79-8)
- Fluconazole Impurity 49 (CAS CATO-C4X-101949)
- 4-Methoxy-2,3-dihydro-1H-inden-1-amine (CAS 52372-96-0)
- 4-((Azetidin-3-yloxy)methyl)picolinonitrile (CAS 1338955-85-3)
- 1-Bromo-2-fluorohexane (CAS 1871-74-5)
- 950455-12-6 N-(2-Methylbenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine MFCD14281799 (CAS 950455-12-6)
- 3-bromo-6-iodo-imidazo[1,2-a]pyridine (CAS 1146615-52-2)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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