Etizolam Impurity 13 CAS 247188-22-3
| CAS No. | 247188-22-3 |
| Molecular Formula | C9H8ClNO2 |
| Molecular Weight | 197.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Etizolam Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Etizolam Impurity 13 (CAS 247188-22-3), a pharmacopoeial impurity reference standard (molecular formula C9H8ClNO2, MW 197.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Etizolam Impurity 13 (C9H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H8ClNO2 |
| Molecular Weight | 197.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Etizolam Standards
Recommended Standards
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- 1-(4-Chloro-3-methoxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256470-62-8)
- 3-Bromo-2,4-dichloro-6-(trifluoromethyl)pyridine (CAS 1214330-62-7)
- 2,4-Dichloro-N-isopropyl-N-(2-(isopropylamino)ethyl)benzenesulfonamide (CAS 946387-07-1)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
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