Opicapone lmpurity 18 CAS CATO-C4X-240418
| CAS No. | CATO-C4X-240418 |
| Molecular Formula | C8H10ClN3O |
| Molecular Weight | 199.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Opicapone lmpurity 18.
Opicapone lmpurity 18 (CAS CATO-C4X-240418) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10ClN3O and a molecular weight of 199.64 g/mol.
The molecular framework of Opicapone lmpurity 18 (C8H10ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Opicapone lmpurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN3O |
| Molecular Weight | 199.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Opicapone Standards
- Opicapone Impurity 75 (CAS >95%)
- Opicapone Impurity 54 (CAS CATO-C4X-240454)
- Opicapone Impurity 44 (CAS CATO-C4X-240444)
- Opicapone impurity 26 (CAS CATO-C4X-240426)
- Opicapone Impurity 4 (CAS 893767-99-2)
- Opicapone impurity 69 (CAS CATO-C4X-240469)
- Opicapone impurity 21 (CAS 1962082-05-8)
- Opicapone impurity 66 (CAS 1639373-19-5)
Recommended Standards
- Sorafenib Impurity 49 (CAS 1446410-29-2)
- 2-(2-chloroanilino)acetohydrazide 2-[(2-chlorophenyl)amino]acetohydrazide (non-preferred name) 2371-29-1 (CAS 2371-29-1)
- N-(6-chloro-3-pyridyl methyl) -n-ethyl-N-nitroso-amine (Mixture of Isomers) (CAS CATO-C4X-24935)
- N'-(6-chloropyridin-2-yl)propionohydrazide (CAS 66999-52-8)
- Ramosetron impurity 31 (CAS CATO-C4X-118231)
- Argatroban Impurity 46 (CAS 57876-69-4)
- Tenofovir Alafenamide Impurity 24 (CAS CATO-C4X-179724)
- 2-(Difluoromethoxy)nicotinic Acid (CAS 1211587-59-5)
- Rimegepant Impurity 41 (CAS CATO-C4X-248741)
- 2-(1-Methylpiperidin-4-yl)azepane (CAS 527674-00-6)
- 2-(2-Bromoallyl)-1-methoxy-4-methylbenzene (CAS 951894-84-1)
- Indapamide Impurity 50 (CAS CATO-C4X-140050)
- 1-(5-Ethoxyoxazol-2-yl)ethanone (CAS 175692-71-4)
- Custom peptides (CAS CATO-CPTD788509)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com