Nintedanib Impurity N7 CAS 894783-61-0
| CAS No. | 894783-61-0 |
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nintedanib Impurity N7 (CAS 894783-61-0) is a certified pharmaceutical impurity reference standard with the molecular formula C30H31N5O4 and a molecular weight of 525.60 g/mol.
Based on its molecular formula C30H31N5O4, Nintedanib Impurity N7 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 525.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nintedanib Impurity N7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Nintedanib Standards
- Nintedanib Impurity N1 (CAS 894783-71-2)
- Nintedanib Impurity N2 (CAS CATO-C4X-12662)
- Nintedanib Impurity N3 (CAS CATO-C4X-12663)
- Nintedanib Impurity N9 (CAS 334951-61-0)
- Nintedanib Impurity 103 (CAS CATO-C4X-1814103)
- Nintedanib Impurity 104 (CAS CATO-C4X-1814104)
- Nintedanib Impurity 105 (CAS CATO-C4X-1814105)
- Nintedanib E-Isomer (CAS 1160294-26-7)
Recommended Standards
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- Edoxaban Impurity 111 (CAS CATO-C4X-1063111)
- Adrenaline EP Impurity E (CAS 36467-25-1)
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- 2-(1H-imidazol-2-yl)-1-(2-methylphenyl)ethan-1-one hydrochloride (CAS 1252206-09-9)
- 2-(4,4-Difluoropyrrolidin-3-yl)acetic acid (CAS 1785372-29-3)
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- 2-Benzamido-N-methyl-N-(1-phenyl-1H-pyrazol-5-yl)benzamide (CAS 88277-69-4)
- 5-(5-Amino-1-phenyl-1H-pyrazol-4-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 1304082-25-4)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com