2-Chloro-4-(2,5-difluorophenyl)pyrimidine CAS 894854-16-1
| CAS No. | 894854-16-1 |
| Molecular Formula | C10H5ClF2N2 |
| Molecular Weight | 226.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Chloro-4-(2,5-difluorophenyl)pyrimidine (C10H5ClF2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 226.61 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Chloro-4-(2,5-difluorophenyl)pyrimidine (CAS 894854-16-1), a certified reference material (molecular formula C10H5ClF2N2, MW 226.61 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-(2,5-difluorophenyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF2N2 |
| Molecular Weight | 226.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-5-hydroxy-2-methylbenzofuran-3-carboxylic acid (CAS 114829-18-4)
- 3-Chloro-6-(2,6-difluorophenyl)pyridazine (CAS 1154600-74-4)
- 4-Chloro-2-(3,4-difluorophenyl)pyrimidine (CAS 1156585-24-8)
- (S)-6-Chloro-4-oxochroman-2-carboxylic acid (CAS 1190606-53-1)
- 6-Chloro-4-hydroxy-7-methoxy-2H-chromen-2-one (CAS 1366396-34-0)
- (R)-6-Chloro-4-oxochromane-2-carboxylic acid (CAS 1372625-50-7)
- 3-(7-Chloro-2H-1,3-benzodioxol-5-yl)prop-2-enoic acid (CAS 1633931-69-7)
- Methyl 5-chloro-3-hydroxybenzofuran-2-carboxylate (CAS 172088-81-2)
Recommended Standards
- 2-Chloro-5-(2,3-difluorophenyl)pyrazine (CAS 1935936-81-4)
- 2-Chloro-4-(3,5-difluorophenyl)pyrimidine (CAS 954218-58-7)
- 2-Chloro-5-(2,6-difluorophenyl)pyrazine (CAS 1935361-09-3)
- 3-(7-Chlorobenzo[d][1,3]dioxol-5-yl)acrylic acid (CAS 852399-81-6)
- (2,3-Dihydrobenzofuran-3-yl)methanol (CAS 68224-03-3)
- 5-Oxo-1-(2-phenoxyethyl)pyrrolidine-3-carboxylic acid (CAS 361985-22-0)
- Piperacillin EP Impurity A Hydrochloride (CAS 40688-84-4)
- (2-Bromophenyl)(cyclopropyl)methanol (CAS 676541-37-0)
- Ethyl 2-((8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)thio)-2,2-difluoroacetate (CAS 1823182-39-3)
- 1-Methyl-1H-pyrrol-3-ol (CAS 107638-08-4)
- [(3-Chlorophenyl)methyl](2-methylpropyl)amine (CAS 893589-64-5)
- 8-Cyano-4-hydroxyquinoline-3-carboxylic acid (CAS 228728-27-6)
- (4S,4'S)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) (CAS 195379-09-0)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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