Trifarotene Impurity 9 CAS 895542-08-2
| CAS No. | 895542-08-2 |
| Molecular Formula | C31H37NO4 |
| Molecular Weight | 487.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Trifarotene Impurity 9.
As a process- or degradation-related impurity, Trifarotene Impurity 9 (CAS 895542-08-2, C31H37NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Trifarotene Impurity 9 (C31H37NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H37NO4 |
| Molecular Weight | 487.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Trifarotene Standards
- Trifarotene Impurity 12 (CAS CATO-C4X-313212)
- Trifarotene Impurity 13 (CAS CATO-C4X-313213)
- Trifarotene (CAS 895542-09-3)
- Trifarotene Impurity 3 (CAS CATO-C4X-31323)
- Trifarotene Impurity 6 (CAS CATO-C4X-31326)
- Trifarotene Impurity 7 (CAS 895543-08-5)
- Trifarotene impurity 22 (CAS CATO-C4X-313222)
- Trifarotene impurity 28 (CAS CATO-C4X-313228)
Recommended Standards
- Fexofenadine EP Impurity F (CAS 185066-33-5)
- Elacestrant Impurity 7 (CAS CATO-C4X-32327)
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
- Solvent Blue 4 (CAS 6786-83-0)
- Pranoprofen Impurity 43 (CAS CATO-C4X-181143)
- Apalutamide Impurity 36 (CAS CATO-C4X-274936)
- Azacitidine Impurity 19 (CAS CATO-C4X-138819)
- 2-(Difluoromethyl)-4-hydroxy-5-methylpyridine-3-carboxylic acid (CAS 1805256-26-1)
- 3-[(2-Chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338396-44-4)
- 2-Amino-N-butylbenzamide (CAS 10494-82-3)
- 2-Amino-3-(1H-pyrazol-4-yl)propanoic acid (CAS 911784-84-4)
- 2-Chloro-4-(difluoromethyl)-5-fluoropyridine-3-sulfonamide (CAS 1805061-89-5)
- 1-((2-Methoxy-4,5-dimethylphenyl)sulfonyl)-1H-pyrazole (CAS 1206087-13-9)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com