Fexofenadine EP Impurity F CAS 185066-33-5
| CAS No. | 185066-33-5 |
| Molecular Formula | C31H37NO4 |
| Molecular Weight | 487.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 487.63 g/mol gives Fexofenadine EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Fexofenadine EP Impurity F (CAS 185066-33-5), a pharmacopoeial impurity reference standard (molecular formula C31H37NO4, MW 487.63 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fexofenadine EP Impurity F (C31H37NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fexofenadine EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H37NO4 |
| Molecular Weight | 487.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Nitrogen Atoms | 1 |
Related Fexofenadine Standards
- Fexofenadine Impurity 11 (CAS 1347311-10-7)
- Fexofenadine Impurity 17 (CAS CATO-C4X-179417)
- Fexofenadine EP Impurity G (CAS 1187954-57-9)
- Fexofenadine Impurity 23 (CAS 1208313-13-6)
- Fexofenadine Impurity 41 (CAS 1795786-25-2)
- Fexofenadine Impurity 16 (CAS CATO-C4X-179416)
- Fexofenadine EP Impurity A (CAS 76811-98-8)
- Fexofenadine Impurity 13 (CAS 1010812-98-2)
Recommended Standards
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
- Trifarotene Impurity 9 (CAS 895542-08-2)
- sPLA2 inhibitor (CAS 393569-31-8)
- Elacestrant Impurity 7 (CAS CATO-C4X-32327)
- Levofloxacin impurity 90 (CAS CATO-C4X-137190)
- Dronedarone Impurity 92 (CAS 141626-35-9)
- Tryptophan EP Impurity A 2HCl (CAS 132685-02-0（free base）)
- Methyl 6-(4-(trifluoromethyl)piperidin-1-yl)nicotinate (CAS 1033463-23-8)
- 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine (CAS 1110656-35-3)
- Diacetyl Monoxime (CAS 57-71-6)
- N-(4-bromophenyl)-2-((5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332161-93-0)
- 1-(5-Fluoro-3-methylbenzofuran-2-yl)ethanone (CAS 56397-39-8)
- 5-Pyridin-3-yl-4-(3-trifluoromethyl-phenyl)-4H-[1,2,4]triazole-3-thiol (CAS 132844-83-8)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com