Trifarotene Impurity 4 CAS CATO-C4X-31324
| CAS No. | CATO-C4X-31324 |
| Molecular Formula | C27H27NO2 |
| Molecular Weight | 397.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Trifarotene Impurity 4 (CAS CATO-C4X-31324, C27H27NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Trifarotene Impurity 4 (C27H27NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 397.51 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H27NO2 |
| Molecular Weight | 397.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Trifarotene Standards
- Trifarotene Impurity 5 (CAS CATO-C4X-31325)
- Trifarotene impurity 16 (CAS CATO-C4X-313216)
- Trifarotene impurity 25 (CAS CATO-C4X-313225)
- Trifarotene Impurity 8 (CAS 895542-96-8)
- Trifarotene impurity 26 (CAS CATO-C4X-313226)
- Trifarotene impurity 21 (CAS CATO-C4X-313221)
- Trifarotene impurity 28 (CAS CATO-C4X-313228)
- Trifarotene impurity 23 (CAS CATO-C4X-313223)
Recommended Standards
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