3,4-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone CAS 898759-65-4

Purity 97%+In StockPharmaceutical Standards
CAS No.898759-65-4
Molecular FormulaC16H12F2O3
Molecular Weight290.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone CAS 898759-65-4 chemical structure

Description

3,4-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone (CAS 898759-65-4) is a high-purity analytical reference standard with the molecular formula C16H12F2O3 and a molecular weight of 290.26 g/mol.

The molecular framework of 3,4-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone (C16H12F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H12F2O3
Molecular Weight290.26 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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