2-(Trifluoromethyl)pyrimidine-4-carbonitrile CAS 916210-03-2
| CAS No. | 916210-03-2 |
| Molecular Formula | C6H2F3N3 |
| Molecular Weight | 173.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Trifluoromethyl)pyrimidine-4-carbonitrile (CAS 916210-03-2), a certified reference material (molecular formula C6H2F3N3, MW 173.10 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 2-(Trifluoromethyl)pyrimidine-4-carbonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 173.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2F3N3 |
| Molecular Weight | 173.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)pyrimidine-5-carbonitrile (CAS 1032229-36-9)
- 4-(Trifluoromethyl)pyrimidine-2-carbonitrile (CAS 1206459-86-0)
- 6-(Trifluoromethyl)pyridazine-3-carbonitrile (CAS 1206524-27-7)
- 4-(Trifluoromethyl)pyrimidine-5-carbonitrile (CAS 1260676-79-6)
- 5-(Trifluoromethyl)pyrazine-2-carbonitrile (CAS 1279818-65-3)
- 6-(Trifluoromethyl)pyrimidine-4-carbonitrile (CAS 1359996-77-2)
- 5-(Trifluoromethyl)pyrimidine-2-carbonitrile (CAS 944905-38-8)
- o-(Trifluoromethyl)-d-serine (CAS 1286761-84-9)
Recommended Standards
- 4,6,7-Trifluoro-1H-imidazo[4,5-c]pyridine (CAS 405230-95-7)
- (3-Aminopropyl)(difluoromethyl)phosphinic acid (CAS 133345-73-0)
- 5-Fluoro-3-nitrobenzene-1,2-diol (CAS 698985-45-4)
- Favipiravir Impurity 1 (CAS CATO-C4X-21021)
- Indapamide EP Impurity C Hydrochloride (CAS 102789-79-7)
- 2-(5-Cyclopropyl-3-(difluoromethyl)-1H-pyrazol-1-yl)acetic acid (CAS 1002032-66-7)
- Cobalt, chloro[[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenaminato]](2-)]-, (SP-5-12)- (CAS 492444-96-9)
- 6-Fluoro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188026-75-6)
- tert-Butyl 5-oxo-1,6-diazaspiro[3.4]octane-1-carboxylate (CAS 1049730-83-7)
- 4-Keto 9-cis Retinoic Acid-d3 (CAS 1185241-31-9)
- (2R,3R,4S,5S,6R)-2-((Benzoyloxy)methyl)-6-(2,2,2-trichloro-1-iminoethoxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate (CAS 183901-63-5)
- 2-(Difluoromethyl)-6-hydroxy-3-nitropyridine (CAS 1806773-61-4)
- 5-(4-Methylphenyl)-1h-pyrazole-4-carboxylic acid (CAS 879996-66-4)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
Why CATO?
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