4-Chloro-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene CAS 918524-44-4
| CAS No. | 918524-44-4 |
| Molecular Formula | C8H5ClF4O |
| Molecular Weight | 228.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene.
4-Chloro-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene (CAS 918524-44-4) is a high-purity analytical reference standard with the molecular formula C8H5ClF4O and a molecular weight of 228.57 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF4O |
| Molecular Weight | 228.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-fluoro-4-(trifluoromethyl)phenyl)hydrazine (CAS 110499-66-6)
- 1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1247205-10-2)
- 1-(2-Chloro-6-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1249544-27-1)
- 2-[Chloro(difluoro)methoxy]-1,3-difluoro-4-methyl-benzene (CAS 1404194-29-1)
- 1-[Chloro(difluoro)methoxy]-2,3-difluoro-4-methyl-benzene (CAS 1404194-41-7)
- (4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)methanol (CAS 1431329-65-5)
- (3-Chloro-2-fluoro-4-(trifluoromethyl)phenyl)methanol (CAS 1431329-79-1)
- 3-Chloro-4-fluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1447606-46-3)
Recommended Standards
- 3-Chloro-2-fluoro-6-(trifluoromethyl)benzyl alcohol (CAS 261763-06-8)
- 6-Chloro-3-fluoro-4-methyl-5-(trifluoromethyl)pyridin-2-amine (CAS 2852769-67-4)
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzyl alcohol (CAS 261763-05-7)
- n-Tetradecane-d30 (CAS 204244-81-5)
- 1-(Imidazo[1,2-a]pyridin-2-ylmethyl)cyclopropane-1-carboxylic acid (CAS 1528590-70-6)
- 1-((2-Chloro-3-nitroquinolin-4-yl)amino)-2-methylpropan-2-ol (CAS 133860-77-2)
- 6-(Ethoxymethylene)-2,2-dimethylcyclohexan-1-one (CAS 1562174-34-8)
- 2-(4-Bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoic acid (CAS 1005584-44-0)
- Ziprasidone Impurity 18 (CAS CATO-C4X-124018)
- 2-amino-6-methylbenzamide (CAS 1885-31-0)
- [2-(cyclopropylmethoxy)phenyl]methanol (CAS 1039931-23-1)
- 6-Methyl-N-(2,2,2-trifluoroethyl)pyrimidin-4-amine (CAS 1248277-37-3)
- 6-(4-Acetylpiperazin-1-yl)-5-methylnicotinic acid (CAS 1355202-04-8)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
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