Citalopram Impurity N1 CAS 920282-75-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.920282-75-3
Molecular FormulaC20H21FN2O
Molecular Weight324.39 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Citalopram Impurity N1 CAS 920282-75-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 324.39 g/mol gives Citalopram Impurity N1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Citalopram Impurity N1 (CAS 920282-75-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21FN2O and a molecular weight of 324.39 g/mol.

Citalopram Impurity N1 (C20H21FN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Citalopram Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H21FN2O
Molecular Weight324.39 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2

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