Lisinopril EP impurity I CAS 927819-64-5
| CAS No. | 927819-64-5 |
| Molecular Formula | C31H41N3O7 |
| Molecular Weight | 567.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 567.67 g/mol gives Lisinopril EP impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Lisinopril EP impurity I (CAS 927819-64-5) is a certified pharmaceutical impurity reference standard with the molecular formula C31H41N3O7 and a molecular weight of 567.67 g/mol.
Structurally, Lisinopril EP impurity I (C31H41N3O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 567.67 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H41N3O7 |
| Molecular Weight | 567.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Lisinopril Standards
- Lisinopril EP Impurity I (CAS CATO-C4X-16819)
- Lisinopril Impurity 25 (CAS 199002-00-1)
- Lisinopril Impurity N (CAS 103300-91-0)
- Lisinopril Impurity 26 (CAS 112246-14-7)
- Lisinopril Impurity 17 (CAS CATO-C4X-168117)
- Lisinopril Impurity 27 (CAS CATO-C4X-168127)
- Lisinopril Impurity 13 (CAS CATO-C4X-168113)
- Lisinopril Impurity 14 (CAS CATO-C4X-168114)
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