Nebivolol Impurity N1 CAS 929706-85-4
| CAS No. | 929706-85-4 |
| Molecular Formula | C29H31F2NO4 |
| Molecular Weight | 495.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Nebivolol Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Nebivolol Impurity N1 (CAS 929706-85-4, C29H31F2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C29H31F2NO4, Nebivolol Impurity N1 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 495.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C29H31F2NO4 |
| Molecular Weight | 495.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 35 (CAS 1199945-26-0)
- Nebivolol Impurity 97 (CAS CATO-C4X-196897)
- Nebivolol Impurity 99 (CAS CATO-C4X-196899)
- Nebivolol-D6 N-Nitroso (CAS CATO-C4X-1968102)
- Nebivolol Impurity 39 (CAS CATO-C4X-196839)
- Nebivolol Impurity 41 (CAS CATO-C4X-196841)
- Nebivolol Impurity 1 (Mixture of Diastereomers) (CAS CATO-C4X-19681)
- Nebivolol Impurity 91 (CAS CATO-C4X-196891)
Recommended Standards
- Octyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-β-D-glucopyranoside (CAS 197390-85-5)
- Octyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-α-D-glucopyranoside (CAS 607353-49-1)
- Pyrene-amido-PEG4-CH2CH2COOH (CAS 1817735-34-4)
- Rosuvastatin Impurity 36 (CAS 147118-40-9)
- Prucalopride Impurity 14 (CAS CATO-C4X-103814)
- Bromfenac Impurity 63 (CAS CATO-C4X-200263)
- Dotinurad Impurity 236 (CAS CATO-C4X-2494236)
- Ethyl 1-hydroxy-1-(trifluoromethyl)-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline-2-carboxylate (CAS 318958-98-4)
- 10,11-Dihydrobenz[a]anthracene (CAS 34501-50-3)
- 4-Nitrobenzenesulfonamide (CAS 6325-93-5)
- 610-29-7 1,4-Benzenedicarboxylic acid, 2-nitro- Nitroterephthalic acid EINECS 210-217-4 2-Nitroterephthalic acid 5-Nitroterephthalic acid NSC 75848 Terephthalic acid, nitro- (CAS 610-29-7)
- 4-Ethylpyrimidin-2-amine (CAS 1193-85-7)
- 52748-86-4 Leucoberbelin blue I DTXSID00328670 (CAS 52748-86-4)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com