Topiroxostat Impurity 47 CAS 93-60-7
| CAS No. | 93-60-7 |
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Topiroxostat Impurity 47.
As a process- or degradation-related impurity, Topiroxostat Impurity 47 (CAS 93-60-7, C7H7NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Topiroxostat Impurity 47 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 137.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Topiroxostat Standards
- Topiroxostat Impurity 4 (CAS 2459-09-8)
- Topiroxostat Impurity 6 (CAS 54-85-3)
- Topiroxostat Impurity 33 (CAS 89830-71-7)
- Topiroxostat Impurity 36 (CAS 35451-46-8)
- Topiroxostat impurity 74 (CAS CATO-C4X-105574)
- Topiroxostat Impurity 3 (CAS 13602-12-5)
- Topiroxostat Impurity 46 (CAS 29181-50-8)
- Topiroxostat Impurity 51 (CAS 98273-47-3)
Recommended Standards
- N-Nitroso Saxagliptin Intermediate (CAS CATO-C4X-104963)
- Sorafenib Impurity 26 (CAS 1693-39-6)
- N-methyl-N-nitrosopyridin-4-amine (CAS 16219-99-1)
- Sorafenib Impurity 28 (CAS CATO-C4X-112428)
- Cyproterone Acetate EP Impurity E (CAS 17184-05-3)
- Moxifloxacin Impurity 33 (CAS 849770-49-6)
- Irinotecan Hydrochloride Trihydrate EP Impurity B (CAS 19685-09-7)
- 1-{[(2-bromophenyl)methylidene]amino}guanidine (CAS 132685-67-7)
- NDD4A44NG2 3612-18-8 1-Ethylpiperidin-4-one EINECS 222-781-9 UNII-NDD4A44NG2 (CAS 3612-18-8)
- ethyl 4-oxo-7-(trifluoromethyl)chromene-2-carboxylate (CAS 2530127-55-8)
- Ethyl 3-Amino-4,4,4-trifluorocrotonate (CAS 372-29-2)
- Methyl 4-(((tert-butoxycarbonyl)amino)methyl)cyclohexane-1-carboxylate (CAS 1609407-74-0)
- 4-Hydroxy-6-(4-methylphenyl)-2,7-diazatricyclo[6.4.0.0,2,6]dodeca-1(12),4,8,10-tetraen-3-one (CAS 938016-20-7)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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