Sorafenib Impurity 28 CAS CATO-C4X-112428
| CAS No. | CATO-C4X-112428 |
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sorafenib Impurity 28 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Sorafenib Impurity 28 (CAS CATO-C4X-112428), a pharmacopoeial impurity reference standard (molecular formula C7H7NO2, MW 137.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sorafenib Impurity 28 (C7H7NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 137.14 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sorafenib Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Sorafenib Standards
- Sorafenib Impurity 26 (CAS 1693-39-6)
- Sorafenib Impurity 24 (CAS 6144-78-1)
- Sorafenib impurity 66 (CAS CATO-C4X-112466)
- Sorafenib Impurity 53 (CAS 611226-36-9)
- Sorafenib Impurity 64 (CAS 99586-65-9)
- Sorafenib Impurity 48 (CAS 5470-22-4)
- Sorafenib Impurity 50 (CAS 1065074-98-7)
- Sorafenib Impurity 67 (CAS 131418-11-6)
Recommended Standards
- Nicotinic Acid EP Impurity A (CAS 3222-47-7)
- Topiroxostat Impurity 6 (CAS 54-85-3)
- 4-methoxynitrobenzene (CAS 1516-21-8)
- Topiroxostat Impurity 47 (CAS 93-60-7)
- Vonoprazan Fumarate Impurity 90 (CAS CATO-C4X-102090)
- Rabeprazole Impurity 45 (CAS CATO-C4X-112145)
- Resmetirom Impurity 34 (CAS CATO-C4X-291234)
- Amoxicillin Impurity 100 (CAS CATO-C4X-1148100)
- cis-Ethyl 5,5-difluoro-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-3-carboxylate (CAS 1428077-58-0)
- (R)-2-(3-Chloro-4-(methylsulfonyl)phenyl)-3-cyclopentylpropanoic acid (CAS 300356-14-3)
- 2-(2,2,2-Tifluoroethyl)isonicotinic acid (CAS 1256809-68-3)
- 2-(((4-Iodophenyl)amino)methyl)phenol (CAS 13159-82-5)
- 2-Chloro-5-(((3-nitropyridin-2-yl)oxy)methyl)thiazole (CAS 339104-65-3)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
Why CATO?
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