Sacubitril-Valsartan Trisodium Salt 2.5hydrate CAS 936623-90-4
| CAS No. | 936623-90-4 |
| Molecular Formula | C24H27N5O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sacubitril-Valsartan Trisodium Salt 2.5hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sacubitril-Valsartan Trisodium Salt 2.5hydrate (CAS 936623-90-4), molecular formula C24H27N5O3C24H28NO5Na2.H2O and molecular weight 908.00 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Sacubitril-Valsartan Trisodium Salt 2.5hydrate (C24H27N5O3C24H28NO5Na2.H2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H27N5O3 C24H28NO5 3*Na 2.5*H2O |
| Molecular Weight | 885.01 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 23.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related Sacubitril Standards
- Sacubitril impurity 41 (CAS 1038924-61-6)
- Sacubitril Impurity 5 (CAS 1038925-00-6)
- Sacubitril Lactam (CAS 1038925-22-2)
- Sacubitril impurity 50 (CAS 1039307-95-3（free base）)
- Sacubitril Sodium Salt (CAS 149690-05-1)
- Sacubitril impurity 54 (CAS 149709-63-7)
- Sacubitril Impurity 55 (CAS 149818-98-4)
- Sacubitril impurity 18 (CAS 1810778-75-6)
Recommended Standards
- (S)-α,α-Diphenylprolinol HCl (CAS 148719-90-8)
- 3-Iodo-1-(methylsulfonyl)-1h-indole (CAS 117637-81-7)
- Ethyl 1-formylcyclohexanecarboxylate (CAS 36873-48-0)
- (3-Fluoro-4'-methyl-[1,1'-biphenyl]-4-yl)boronic acid (CAS 1698890-39-9)
- 4-Amino-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)benzenesulfonamide (CAS 1304628-20-3)
- 6-Aminopyrazolo[1,5-a]pyrimidine (CAS 1018125-39-7)
- (1-(Piperidin-1-yl)cyclohexyl)methanamine (CAS 41805-36-1)
- trans-2-methylazetidine-3-carboxylic acid (CAS 2883822-11-3)
- 4-(4-Amino-2,5-dimethoxyphenyl)-2,5-dimethoxyaniline hydrochloride (CAS 1235439-32-3)
- Semaglutide impurity 29 (CAS 110990-08-4)
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