Montelukast EP Impurity F CAS 937275-23-5
| CAS No. | 937275-23-5 |
| Molecular Formula | C34H32ClNO3S |
| Molecular Weight | 570.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Montelukast EP Impurity F (CAS 937275-23-5), a pharmacopoeial impurity reference standard (molecular formula C34H32ClNO3S, MW 570.14 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Montelukast EP Impurity F (C34H32ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Montelukast EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C34H32ClNO3S |
| Molecular Weight | 570.14 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Montelukast Standards
- Montelukast EP Impurity B (CAS 918972-54-0)
- Montelukast Impurity 4 (CAS 1772578-77-4)
- Montelukast Impurity C167 (CAS 866923-62-8)
- Montelukast Impurity 2 (CAS CATO-C4X-10312)
- Montelukast Amide (CAS 866923-63-9)
- Montelukast EP Impurity H (CAS 851755-56-1)
- Montelukast Impurity 24 (CAS CATO-C4X-103124)
- Montelukast (CAS 158966-92-8)
Recommended Standards
- N-Acetyl-di-O-acetyl KRP-203 (CAS 951238-25-8)
- Loratadine Impurity 50 (CAS CATO-C4X-142650)
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- 2,2-Dichloro-1-(3,5-dimethyl-1H-pyrazol-1-yl)ethanone (CAS 540531-52-0)
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- 4,5-Diiodophthalic acid (CAS 82679-28-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com