Difamilast Impurity 8 CAS 2103190-85-6
| CAS No. | 2103190-85-6 |
| Molecular Formula | C21H20F2N2O6 |
| Molecular Weight | 434.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Difamilast Impurity 8 (C21H20F2N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Difamilast Impurity 8 (CAS 2103190-85-6), a pharmacopoeial impurity reference standard (molecular formula C21H20F2N2O6, MW 434.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Difamilast Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20F2N2O6 |
| Molecular Weight | 434.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difamilast Standards
- Difamilast Impurity 5 (CAS 2103190-81-2)
- Difamilast Impurity 3 (CAS 937782-02-0)
- Difamilast Impurity 1 (CAS 1574285-40-7)
- Difamilast (CAS 937782-05-3)
- Difamilast Impurity 10 (CAS 2103190-58-3)
- Difamilast Impurity 6 (CAS 937782-01-9)
- Difamilast Impurity 2 (CAS 2103190-94-7)
- Difamilast Impurity 4 (CAS 2103190-65-2)
Recommended Standards
- 10-Hydroxyaloin A (CAS 134863-91-5)
- Tenofovir alafenamide Impurity 14 (CAS 1234081-04-9)
- 10-Hydroxyaloin B (CAS 134863-92-6)
- 2-(difluoro(3,4,5-trifluorophenoxy)methyl)-1,3-difluoro-5-((1s,4r)-4-propylcyclohexyl)benzene (CAS 208338-62-9)
- Vonoprazan Impurity 32 (CAS 2514742-82-4)
- Chlortetracycline EP Impurity A (CAS 14297-93-9)
- Minodronic Acid Impurity 21 Disodium salt (CAS CATO-C4X-124121)
- 4-Pentylbenzamide (CAS 138913-07-2)
- 2-Methyl-5-(tributylstannyl)thiazole (CAS 223418-75-5)
- Acipimox Impurity 19 (CAS CATO-C4X-186619)
- Ethyl 2-amino-2-(2-nitrophenyl)acetate (CAS 791050-91-4)
- N-(tert-Butoxycarbonyl)-D-2-phenylglycine (CAS 33125-05-2)
- (S)-2-Amino-2-(4-(trifluoromethyl)phenyl)acetic acid hydrochloride (CAS 2231023-63-3)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com