Methylprednisolone Acetate EP Impurity A (20R Isomer) CAS 93963-74-7
| CAS No. | 93963-74-7 |
| Molecular Formula | C24H34O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methylprednisolone Acetate EP Impurity A (20R Isomer) (CAS 93963-74-7), a pharmacopoeial impurity reference standard (molecular formula C24H34O6, MW 418.53 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Methylprednisolone Acetate EP Impurity A (20R Isomer) (C24H34O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 418.53 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H34O6 |
| Molecular Weight | 418.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
Related Methylprednisolone Standards
- Methylprednisolone Impurity 72 (CAS 1012306-79-4)
- Methylprednisolone impurity 96 (CAS 103302-98-3)
- Methylprednisolone Impurity 57 (CAS 1048031-80-6)
- Methylprednisolone Acetate EP Impurity J (CAS 1048031-82-8)
- Methylprednisolone impurity 87 (CAS 105500-05-8)
- Methylprednisolone impurity 82 (CAS 106502-98-1)
- Methylprednisolone Acetate EP Impurity K (CAS 115321-98-7)
- Methylprednisolone Hydrogen Succinate EP Impurity D (CAS 119657-85-1)
Recommended Standards
- Elagolix Impurity 35 (CAS CATO-C4X-206835)
- Cefdinir USP Impurity A (CAS 178949-03-6)
- Eltrombopag Impurity 90 (CAS CATO-C4X-119890)
- 1-ethyl-3-isocyanato-1H-indole (CAS 1082325-97-0)
- 2-​Formamidoacetamide (CAS 4238-57-7)
- Sitagliptin Impurity 167 (CAS 1840966-95-1)
- Ethyl 2-(difluoromethyl)-8-fluoroimidazo[1,2-a]pyridine-3-carboxylate (CAS 2451256-49-6)
- O,O-Tepp (CAS 107-49-3)
- 4-(sec-Butyl)-6-chloro-N-ethyl-1,3,5-triazin-2-amine (CAS 62733-75-9)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com