(S)-Ruxolitinib CAS 941685-37-6
| CAS No. | 941685-37-6 |
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-Ruxolitinib (CAS 941685-37-6), molecular formula C17H18N6 and molecular weight 306.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-Ruxolitinib (C17H18N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (S)-Ruxolitinib under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related S Standards
- rac-Ruxolitinib (CAS 941688-05-7)
- Ruxolitinib Hemifumarate (CAS 2803478-47-7)
- Ruxolitinib (CAS 941678-49-5)
- Ruxolitinib Impurity 23 (CAS CATO-C4X-205823)
- Ruxolitinib Impurity 79 (CAS 941678-60-0)
- Ruxolitinib Impurity 111 L-Tartrate (CAS 2169914-36-5)
- Ruxolitinib Impurity 126 (CAS CATO-C4X-2058126)
- Ruxolitinib Impurity 8 (CAS 2606144-45-8)
Recommended Standards
- tert-Butyl 2-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-3-yl)acetate (CAS 1003209-11-7)
- Ethyl 2-((4-(1-ethyl-3-methyl-1h-pyrazol-4-yl)pyrimidin-2-yl)thio)acetate (CAS 1006340-77-7)
- Nilotinib Impurity 20 (CAS CATO-C4X-125620)
- Ethyl 2-((4-(1,3,5-trimethyl-1h-pyrazol-4-yl)pyrimidin-2-yl)thio)acetate (CAS 1006353-04-3)
- 4-((2-Chloropyrimidin-4-yl)amino)cyclohexan-1-ol (CAS 1248118-63-9)
- 2-(3,5-Dichlorophenoxy)acetonitrile (CAS 103140-12-1)
- (E)-3-(3,5-Dimethylphenyl)prop-2-en-1-amine (CAS 1965315-91-6)
- 5-Chloro-1-((2-hydroxyethoxy)methyl)pyrimidine-2,4(1H,3H)-dione (CAS 81777-50-6)
- Ethyl 2-(3-phenylthioureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 42076-12-0)
- 2-(4-Bromo-2-fluorophenyl)-6-methoxypyridine (CAS 1187170-02-0)
- 2-Chloro-N,N-dimethylbutanamide (CAS 59843-83-3)
- Methyl 4-(dimethylphosphoryl)thiophene-2-carboxylate (CAS 2613385-91-2)
- 1-Methyl-4-(vinylsulfonyl)-1H-pyrazole (CAS 1707747-13-4)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com