Cetirizine Dihydrochloride EP Impurity B CAS 942193-17-1
| CAS No. | 942193-17-1 |
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | 344.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Cetirizine Dihydrochloride EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 344.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Cetirizine Dihydrochloride EP Impurity B (CAS 942193-17-1, C19H21ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cetirizine Dihydrochloride EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | 344.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine Impurity N19 (CAS 113740-61-7)
- Cetirizine Impurity 37 (CAS CATO-C4X-158237)
- Cetirizine EP Impurity F (CAS 83881-53-2)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- Cetirizine Impurity 26 (CAS CATO-C4X-158226)
- Cetirizine Impurity 36 (CAS CATO-C4X-158236)
- Cetirizine Impurity 35 (CAS CATO-C4X-158235)
- Cetirizine USP Related Compound C (CAS 83881-37-2)
Recommended Standards
- N-[2-Amino-4-(4-methylpiperazino)phenyl]-3-chlorobenzenecarboxamide (CAS 439107-46-7)
- Clozapine EP Impurity D (CAS 65514-71-8)
- N-(Benzo[d]thiazol-6-yl)-3-chlorobenzo[b]thiophene-2-carboxamide (CAS 942002-44-0)
- Bifonazole Impurity 22 (CAS CATO-C4X-156022)
- Iopromide impurity 15 (CAS CATO-C4X-183215)
- Adapalene impurity 17 (CAS 911110-93-5)
- Lifitegrast Impurity 87 (CAS CATO-C4X-240987)
- 4-Bromo-2-chloro-5-methylbenzenethiol (CAS 1349708-73-1)
- 2-(Dimethylamino)-6-fluorobenzonitrile (CAS 96994-73-9)
- 3-(pyridin-2-ylamino)propanoic acid hydrochloride (CAS 1181458-18-3)
- N-Ethyl-4-methoxy-N-phenylbenzenesulfonamide (CAS 5343-90-8)
- 2-Nitroselenophene (CAS 15429-04-6)
- 2-chloroethyl diethyl phosphate (CAS 5630-71-7)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com