Cetirizine EP Impurity F CAS 83881-53-2
| CAS No. | 83881-53-2 |
| Molecular Formula | C21H26N2O3 |
| Molecular Weight | 354.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Cetirizine EP Impurity F (CAS 83881-53-2), a pharmacopoeial impurity reference standard (molecular formula C21H26N2O3, MW 354.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Cetirizine EP Impurity F (C21H26N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H26N2O3 |
| Molecular Weight | 354.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine Impurity 37 (CAS CATO-C4X-158237)
- Cetirizine Dihydrochloride EP Impurity B (CAS 942193-17-1)
- Cetirizine Impurity N19 (CAS 113740-61-7)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- Cetirizine Impurity 26 (CAS CATO-C4X-158226)
- Cetirizine USP Related Compound C (CAS 83881-37-2)
- Cetirizine EP Impurity C (CAS 83881-59-8)
- Cetirizine (CAS 83881-51-0)
Recommended Standards
- 1,2:3,4-Di-O-cyclohexylidene-5-O-methyl-L-chiro-inositol 6848-53-9 CTK8F2865 (CAS 6848-53-9)
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- t-Butyl N-Cbz-DL-Phenylalaninamide (CAS 4124-61-2)
- N-Nitroso Bisoprolol (CAS 2820170-76-9)
- Daptomycin Impurity 42 (CAS CATO-C4X-137842)
- Rivastigmine impurity 34 (CAS CATO-C4X-138434)
- Nicorandil Impurity 49 2Nitrat (CAS 2365474-06-0)
- 4-Bromo-3-methyl-N-propylbenzenesulfonamide (CAS 794570-18-6)
- 8-Hydroxy-1-methylquinolin-2(1H)-one (CAS 59828-11-4)
- 2-Phenylpropane-2-thiol (CAS 16325-88-5)
- 2-[(Fmoc-amino)methyl]benzoic Acid (CAS 219640-94-5)
- 2-Trifluoromethanesulfonylaniline (CAS 17095-18-0)
- Methyl 4-hydroxy-6-(2-methoxyphenyl)-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxylate (CAS 1403233-53-3)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com